Anpa'o Locke is an Afro-Indigenous writer, filmmaker, and curator who is Húŋkpapȟa Lakota and Ahtna Dené (Village of Tazlina), born in the Standing Rock Nation and now residing in Albuquerque, New Mexico.

Anpa'o was a 2023 Native Lab Fellow and a 2022 Full Circle Fellow at the Sundance Institute. She holds a degree in Film Studies from Mount Holyoke College, where she developed a love for 35mm, Super 8, and 16mm. Her notable work includes curating Imagining Indigenous Cinema at the UCLA Film & Television Archives in 2023, a groundbreaking film series that highlighted over 40 films by US-based Indigenous artists in the post-Standing Rock era.

Her upcoming short film Kawá was developed at the Sundance Native Labs.